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癌基因及相关基因国家重点实验室
发表时间:2012-09-10阅读次数:49次

 

癌基因及相关基因国家重点实验室

网址

www.shsci.org

地址

上海市斜土路2200弄25号

邮编

200032

电话

021-64436515

传真

021-64177401

批准单位

国家计委

批准日期

1985年8月

实验室主任

王红阳

电子邮箱

nlorg@sh163.net

研究方向及特色

癌基因及相关基因国家重点实验室是我国生命科学领域第一个批准建设的国家重点实验室。国家重点实验室在肝癌功能基因组研究方面,发现了一批具有重要功能和应用前景的新基因,提出肿瘤是一种系统性疾病的新理念,开拓了以系统生物学观念研究肿瘤的新领域;在肿瘤转化医学研究方面,尤其在肿瘤的生物治疗领域取得了创新性发现和成果。

主要研究方向:

  1. 以肝癌为主要对象,研究与确定癌发生发展相关的癌基因、抑癌基因及其它调控细胞生长的基因群;
  2. 以系统生物学的理念,对肝癌等恶性肿瘤的各种组学进行综合性研究,以及从神经递质、免疫、激素对肿瘤的系统性调控及其失常进行研究,探索癌发生发展的机理;
  3. 基于以上研究,研究肿瘤诊断、治疗与预防的新途径。

 

主要大型

仪器设备

1. 流式细胞分析分选系统        2. 流式细胞仪

3. 多功能荧光分光光度计        4. 全自动免疫组化染色仪

5. ABI7300 型荧光定量PCR仪    6. 激光显微切割仪

7. 生物分析仪                  8. 倒置荧光显微镜

9. 正置荧光显微镜              10.微孔板扫描分光光度计

11.连续光谱多功能酶标仪        12.亲和传感器

State Key Laboratory for Oncogenes and Related Genes

Research Directions & Characteristics:

State Key Laboratory for Oncogenes & Related Genes (SKLORG), affiliated to Shanghai Cancer Institute and Shanghai Jiaotong University, was founded in 1985 and approved to launch in 1987.

The current director of the laboratory is Professor Hongyang Wang, academician of Chinese Academy of Engineering. Professor Shengli Yang, academician of Chinese Academy of Engineering, is the chair of the academic committee which includes 15 distinguished experts and scholars specialized in molecular biology, molecular genetics, immunology, endocrinology, and cell biology. Professor Jianren Gu, academician of Chinese Academy of Engineering, is the former director and academic committee chair of State Key Laboratory, and honorary president of Shanghai Cancer Institute.

Based on the principles of systems biology and approaches of genomics, proteomics, metabonomics and molecular cell biology, the research projects in SKLORG are mainly focused on: 1, identifying novel genes related to hepatocellular carcinoma, i.e. oncogenes, tumor suppressor genes, apoptotic genes, DNA repair genes and other therapeutic genes; 2, elucidating the deregulation of neurotransmitters / immune / endocrine systems in host-microenvironment-cells interaction in carcinogenesis and cancer progression including metastasis; 3, developing the novel methods for early diagnosis, treatment and prevention. With the scientific and technical advantages and long-term research experiences, the State Key Laboratory’s aim is to establish a comprehensive cancer research center with high international reputation for the basic and translational research and postgraduate education.

Address:

25/Ln 2200, Xietu Rd, Shanghai 200032, P.R.China

Website:

www.shsci.org

Director:

Prof. Hong-Yang WANG

Tel:

+86 21 6443 6515

Email:

nlorg@sh163.net

 

 

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